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S&P500 and Dow Jones: UnitedHealth Drops 19%, Eli Lilly Jumps on Trial Results

By:
James Hyerczyk
Updated: Apr 17, 2025, 14:51 GMT+00:00

Key Points:

  • UnitedHealth collapses 19% on earnings miss, dragging Dow futures down over 400 points in Thursday’s premarket trade.
  • S&P 500 and Nasdaq-100 futures rise as investors rotate into healthcare and tech after Wednesday’s broad market selloff.
  • Eli Lilly surges 11% on strong phase-three trial data for its weight-loss and diabetes pill, boosting healthcare sentiment.
S&P500 and Dow Jones:  UnitedHealth Drops 19%, Eli Lilly Jumps on Trial Results
In this article:

S&P Futures Rebound While Dow Struggles On UnitedHealth Collapse

Daily E-mini S&P 500 Index

U.S. equity futures were mixed Thursday as investors sought to claw back losses from the prior session’s broad selloff. S&P 500 futures rose 0.3%, while Nasdaq-100 futures gained 0.6%. Dow futures dropped 403 points, or 1%, driven by a nearly 19% plunge in UnitedHealth following disappointing earnings. The move capped a turbulent week heading into Friday’s market closure for Good Friday.

Why Is The Dow Underperforming?

Daily UnitedHealth Group Incorporated

UnitedHealth delivered weaker-than-expected Q1 results, reporting adjusted earnings of $7.20 per share on revenue of $109.6 billion—missing both top and bottom-line estimates. The insurer also cut its full-year guidance, sparking a steep selloff that alone knocked Dow futures down over 400 points. With UnitedHealth as one of the Dow’s heaviest components, the index is on pace for a weekly loss exceeding 1%.

Where Are Traders Finding Strength?

Daily Taiwan Semiconductor Manufacturing Company Ltd

The Nasdaq showed relative strength, supported by strong earnings from Taiwan Semiconductor. Shares of TSM jumped 3% after beating Q1 expectations and maintaining its full-year outlook despite tariff concerns.

Daily Eli Lilly and Company

Eli Lilly surged 11% following positive phase-three trial results for a weight-loss and diabetes pill, bolstering sentiment in healthcare. While Nvidia remained flat premarket, it had slumped nearly 7% the prior day after revealing a $5.5 billion charge tied to U.S. export controls on GPUs.

Which Other Stocks Are On The Move?

Daily Hertz Global Holdings, Inc

Hertz rallied another 16%, extending its surge after Bill Ackman’s Pershing Square disclosed a sizable stake. The stock is up over 70% across two sessions. In housing, D.R. Horton dropped more than 3% after posting Q2 earnings and revenue below consensus. Alcoa slipped over 2% as Q1 revenue missed forecasts at $3.37 billion, although earnings topped estimates.

What’s Driving Broader Market Sentiment?

Markets remain sensitive to policy signals. Fed Chair Jerome Powell warned Wednesday that proposed tariffs could drive inflation higher, potentially complicating the Fed’s dual mandate. His comments triggered a steep selloff, especially in tech, with the Nasdaq falling over 3% on the day. That decline pushed the index closer to bear market territory and added to growing fears of stagflation and recession.

What’s The Outlook Heading Into The Holiday Break?

All three major indexes are tracking for weekly losses, with the Nasdaq down 2.5%, the S&P off over 1%, and the Dow similarly lower. Traders are watching corporate earnings, Powell’s rhetoric, and global trade risks closely. Tech and healthcare are offering relative support, but pressure on mega-caps and signs of slowing consumer demand suggest continued chop ahead.

More Information in our Economic Calendar.

About the Author

James Hyerczyk is a U.S. based seasoned technical analyst and educator with over 40 years of experience in market analysis and trading, specializing in chart patterns and price movement. He is the author of two books on technical analysis and has a background in both futures and stock markets.

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